Stemergy MetaBalance

• Specially formulated to improve insulin sensitivity, glucose tolerance, and insulin signaling
• Proven in human clinical trials to have regenerative potential via hematopoietic and
mesenchymal stem cell proliferation and release into peripheral circulation for use in
body target sites
• Supports and nourishes cells throughout the body
• Cells starved by aberrant glucose utilization may be nourished by this formulation
• Suitable for anyone that wants to regulate and stablize their blood sugar level on a daily basis
• This product is not a replacement for insulin. It has naturally-induced cellular detoxification and
reactive oxygen species that support the healthy proliferation and release of circulating
mesenchymal cells that could target and sustain the pancreas (that produce, store and release
the hormone insulin). It releases paracrine factors to further modify an aberrant/toxic
microenvironment making it more conducive to regenerate insulin-producing beta cells.
• This formulation can also help minimize the damaging effects of associated progressive disease.
• Exhibits anti-inflammatory activity
• Supports blood sugar and lipid levels in humans

Type 2 diabetes

There are about 500 million people in the world with Type 2 diabetes. Type 2 diabetes is a chronic condition in which the body fails to properly use and store glucose. Instead of converting sugar into energy, it backs up in the bloodstream and causes a variety of symptoms.

Type 2 diabetes results when the body doesn’t produce enough insulin and/or is unable to use insulin properly (insulin resistance). This form of diabetes usually occurs in people who are over 40 years of age, overweight, and have a family history of diabetes, although it is now increasingly found in younger people. Type 2 diabetes can be caused by a variety of factors: being overweight, being physically inactive, or your body’s inability to properly use the insulin it produces. In addition, those who have been previously identified as having impaired fasting glucose or impaired glucose tolerance are also at risk. In some cases of type 2 diabetes, there are no symptoms and people can live for months, even years, without knowing they have the disease.

Risk factors for type 2 diabetes include obesity, high cholesterol, high blood pressure, and physical inactivity. The risk of developing type 2 diabetes also increases as people grow older. Women who develop diabetes while pregnant (gestational diabetes) are more likely to develop type 2 diabetes later in life. Currently, there is no conventional medicine cure for type 2 diabetes. If left untreated, it can lead to a number of damaging complications such as heart attacks, strokes, blindness, kidney failure, and blood vessel disease that may require an amputation, nerve damage, and impotence in men. The aim of treatment is to normalize the blood glucose in an attempt to prevent or minimize complications.

People with type 2 diabetes may experience marked hyperglycemia, but many do not require insulin injections and can be treated with diet, exercise, and oral hypoglycemic drugs. Type 2 diabetes is often treated with oral medication because many people with Type 2 diabetes make some insulin on their own. The pills people take to control type 2 diabetes do not contain insulin.  Instead, medications such as metformin, sulfonylureas, alpha-glucosidase inhibitors and many others are used to make the insulin that the body still produces more effective.  Some people with type 2 diabetes are treated with insulin – either injectable or via insulin pump.

Stemergy offers a formulation specifically aimed at managing blood glucose levels in people with Diabetes Type 2 using natural substances capable of producing required sugar-lowering/utilization effects. Stemergy formulations are not a replacement for insulin. They are considered to be complimentary to current standard of care.  Once the effect of the product is known to the patient and verified by a physician, the formulation may be incorporated into management strategies with possible reduction of insulin or other medication dependence. Interestingly, there is evidence that herbal supplementation for disease management results in some possible functional re-acquisition of pancreatic beta cell insulin production through either realignment, re-sensitization or proliferation of these cells.

In non-insulin dependent diabetes (NIDDM), StemErgy Gluco Metabolic 2 has been designed to improve glucose sensitivity and related lipogenic metabolics precluding a progression to insulin and possibly reconstituting beta cell activity and return to normalcy.

Formulation Overview:  Ingredients in StemErgy MetaBalance:

• Proven in human clinical trials to have regenerative potential via hematopoietic and mesenchymal stem cell proliferation and release into peripheral circulation for use in body target sites.
• Supports and nourishes cells throughout the body. Cells starved by aberrant glucose utilization may be nourished by this formulation.
• Naturally-induced cellular detoxification and reactive oxygen species scavenging supports the healthy proliferation and release of circulating mesenchymal cells that could target and sustain the pancreas (that produce, store and release the hormone insulin) where they would release paracrine factors to further modify an aberrant/toxic microenvironment making it more conducive to some regeneration of insulin-producing beta cells.
• This formulation also can help minimize the damaging effects of associated progressive disease.
• Contains highly effective blood glucose lowering compounds.
• Exhibits strong anti-diabetic, anti-oxidant and astringent properties which may moderate inflammation
• It is also reported to have cell protective and regenerative properties, effects which have been attributed to the flavonoid content in the plant formulation.
• Complete restoration of normal insulin secretion and regeneration of beta cells have been reported with ingredients in this formulation in various experimental models.
• Possesses strong anti-hyperlipidemic activity
• Lower glycemic activity is achieved by suppression of enzymes glucose-6-phosphatase and fructose-1,6-bisphosphatase in the liver.
• Improves insulin sensitivity, glucose tolerance, and insulin signaling.
• May improve insulin resistance by influencing peroxisome proliferator-activated receptor (PPAR) alpha and PPAR gamma expression and by modulating the phosphorylation status of insulin receptor and its downstream signaling molecules. A recent study showed that the preventive effects of ingredients in our formulation against insulin resistance are via modulation of nuclear factor (NF-kappa B) and phospho-c-Jun N-terminal kinase (JNK) pathways.
• May also help weight loss by reducing lipogenesis in adipose tissue. Animals that were fed with ingredients in our formulation showed lower fatty acid synthase. The ingredients also affect fat and carbohydrate metabolism by stimulating thyroid hormones and adiponectin, and by enhancing the activity of AMP-activated protein kinase (AMPK).
• In another study, ingredients were shown to prevent inflammation and oxidative stress, modulate mitochondrial activity, suppress apoptosis activation, and inhibit lipid accumulation during the development of fatty liver. Each attribute of just one of our ingredients has demonstrated support in the diabetic control goal of glucose regulation, insulin re-sensitization and inhibits lipid metabolism.
• Exhibits anti-inflammatory activity by inhibiting nitric oxide production via inhibition of NF-kappaB.
• Inhibits hepatic HMG-CoA reductase activity and reduces the level of blood lipids in animals and humans.
• An isolate extracted from one of the ingredients in our formulation has been shown to mimic insulin by activating insulin receptors and has been shown in some clinical trials to lower blood glucose and lipids levels.
• Our formulation has antioxidant, antibacterial, hepatoprotective, cardioprotective, radioprotective, antiulcerogenic, antitumor, analgesic, antidiabetic, and antihyperlipidemic properties.
• The activity of our ingredients have often been attributed to their antioxidant constituents, such as ascorbic acid, polyphenols, flavonoids, and tannin.
• Clinical data are limited to a few studies that show benefit in patients with uremia (accumulation of constituents in the blood that are normally eliminated in the urine) by reducing oxidative stress; improving HDL and lower LDL-cholesterol levels in diabetic patients; and lowering lipid levels and blood pressure in patients with hyperlipidemia. Supplementation with just one of our ingredients was shown to lower multiple risk factors associated with cardiovascular disease in overweight adults.
• Contains an essential mineral that plays a significant role in vascular and metabolic biology as well as numerous biochemical reactions. As a cofactor of all reactions involving ATP transfer, it is a major determinant of insulin and glucose metabolism, critical to carbohydrate metabolism, and regulates the activity of all enzymes involved in phosphorylation reactions. These vascular and metabolic mechanisms are echoed by observed relationships between a deficiency and oxidative stress, proinflammatory states, endothelial dysfunction, platelet aggregation, insulin resistance, and hyperglycemia.
• This essential mineral also helps regulate blood pressure and enzymes such as those that control intracellular calcium and potassium, and is essential for normal heart functioning. Both dietary and supplementation sources have demonstrated benefits for ailments such as heart disease and diabetes.
• It is associated with reduced mortality from cardiovascular disease, especially for women. It is also associated with reduced risk of sudden cardiac death (SCD) and may help reduce the risk of ischemic stroke, metabolic syndrome, type 2 diabetes and insulin resistance, asthma, and osteoporosis.
• Ingredients in our formulation may increase survival in patients with heart failure, and improve insulin sensitivity in healthy adults.
• In a study of overweight individuals, supplementation resulted in changes in gene expression and other positive effects on metabolic pathways.

As you can see we have created a synergistic formulation that can be very powerful in its benefits for balancing metabolic syndrome and all its resulting deleterious effects.